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For main stem intubation, the ETTshould be 0.5 mm smaller than what would nor-mally be used based on the patient’s age (usuallya 3.0–3.5 ETT in neonates). Immediately after surgery and through-out the ?rst week, the ?rst choice of drugs is an opioidwith a benzodiazepine. ZnO is usually the most toxicamong those tested and dissolution to ionic zinc is the mainmode of action.
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Metabolism parameters(glucuronide conjugation and hydrolysis) were scaled byadjusting the adult value by the ratio of the fetal:adult liverweight, since the fetal liver weight is not linearly corre-lated with body weight.
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